When you you try to install iTunes on your Windows PC, you get an error that matches or is similar to the following:

C:\Documents and Settings\username\Local Settings\Temporary Internet Files\Content.IE5\crazynumber\iTunes801Setup[1].exe is not a valid Win 32 application.

To try to fix this issue, preform the following steps:

1. Delete all of the versions of the iTunes installation program from your computer. Then download a new copy. When prompted, Save the file to the Desktop instead of Running or Opening the file.

2. Open Internet Explorer.

3. Select Tools > Delete Browsing History.

4. Hit the Delete files… under the Temporary Internet Files section.

5. Click Yes when prompted. IE will then work on clearing the files.

6. Click Close.

7. Close Internet Explorer.

8. Install your newly downloaded copy of the iTunes setup program from the file on your Desktop.

See also: iTunes: Windows reports that iTunesSetup.exe is not a “valid Win32 application”